Pierson Prioleau: Pick #110 in the 1999 NFL Draft

Pierson Prioleau is a former safety out of Virginia Tech, selected by the San Francisco 49ers with the 110th overall pick (round 4) in the 1999 NFL Draft. He played 160 regular-season games from 1999 to 2010, with the San Francisco 49ers, Buffalo Bills, Washington Redskins, Jacksonville Jaguars and New Orleans Saints.

Draft Details

Year

1999

Round

Round 4

Pick

110th overall

Team

San Francisco 49ers

Position

S

College

Virginia Tech

Pierson Prioleau Career Stats

Primary starter for 1 season.

Defense

Season	Team	G	Solo	Ast	TFL	Sacks	QB Hits	INT	PD	FF
1999	SF	13	33	9	1	0	0	0	10	1
2000	SF	13	37	11	0	0	0	1	3	2
2001	BUF	6	23	8	1	1	1	0	1	1
2002	BUF	16	54	22	2	1	1	0	4	0
2003	BUF	15	23	13	0	0.5	0	0	5	1
2004	BUF	15	18	14	0	0.5	0	0	1	0
2005	WAS	14	37	4	0	3	0	0	4	2
2007	WAS	14	24	14	0	0	0	0	0	0
2008	JAX	9	23	1	0	0	0	0	1	0
2009	NO	13	26	3	0	0	0	0	1	0
2010	NO	10	12	5	0	0.5	1	0	0	0
Career		138	310	104	4	6.5	3	1	30	7

G = games with at least one recorded statistic; the career games total in the summary above includes every game played.

Source: nflverse · Updated Sep 28, 2026

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1	1	CLE	Tim Couch	QB	Kentucky
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1	4	IND	Edgerrin James	RB	Miami
1	5	NO	Ricky Williams	RB	Texas
1	6	LA	Torry Holt	WR	N.C. State
1	7	WAS	Champ Bailey	CB	Georgia
1	8	ARI	David Boston	WR	Ohio State
1	9	DET	Chris Claiborne	LB	USC
1	10	BAL	Chris McAlister	DB	Arizona, Mt. San Antonio