What College Has Produced the Most NFL Draft Picks?

USC tops the list with 332 players drafted across the 1967–2025 classes covered here.

Top Five Programs

1. USC — 332 drafted
2. Ohio State — 315 drafted
3. Notre Dame — 293 drafted
4. Michigan — 291 drafted
5. Penn State — 289 drafted

Players who transferred are counted for every school they attended, so someone who began at a junior college and finished at a major program appears under both.