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| Rd | Pick | Team | Player | Pos | College |
|---|---|---|---|---|---|
| 1 | 1 |  CLE |
 Baker Mayfield |
QB | Oklahoma, Texas Tech |
| 1 | 2 |  NYG |
 Saquon Barkley |
RB |  Penn State |
| 1 | 3 |  NYJ |
 Sam Darnold |
QB |  USC |
| 1 | 4 | CLE |
 Denzel Ward |
CB |  Ohio State |
| 1 | 5 |  DEN |
 Bradley Chubb |
OLB | N.C. State |
| 1 | 6 |  IND |
 Quenton Nelson |
G |  Notre Dame |
| 1 | 7 |  BUF |
 Josh Allen |
QB | Wyoming, Reedley |
| 1 | 8 |  CHI |
 Roquan Smith |
ILB |  Georgia |
| 3 | 1 | NYG |
 Sam Beal |
DB | Western Michigan |
| 6 | 1 |  WAS |
 Adonis Alexander |
DB |  Virginia Tech |